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Fig. 7 | Experimental Hematology & Oncology

Fig. 7

From: Suppression of A-to-I RNA-editing enzyme ADAR1 sensitizes hepatocellular carcinoma cells to oxidative stress through regulating Keap1/Nrf2 pathway

Fig. 7

ADAR1 deficiency exacerbates the damage of tBHP on intracellular antioxidant system as well as destroys cellular morphology in HCC. A–F Measurement of intracellular content of GSH and MDA as well as activity of SOD in HepG2 and SMMC-7721 cells with tBHP administration and/or sh-ADAR1 transfection. G TEM images of changes in cellular morphology of HepG2 and SMMC-7721 cells with or without sh-ADAR1 transfection. Bar, 2 μm. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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Experimental Hematology & Oncology

ISSN: 2162-3619

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