Fig. 5From: Suppression of A-to-I RNA-editing enzyme ADAR1 sensitizes hepatocellular carcinoma cells to oxidative stress through regulating Keap1/Nrf2 pathwayADAR1 deficiency enhances the inhibiting effect of oxidative stress agonist tBHP on HCC cell proliferation and the promoting effect on apoptosis. A–D EdU staining for proliferation of HepG2 and SMMC-7721 cells with tBHP administration and/or sh-ADAR1 transfection. Bar, 20 μm. E–H Flow cytometry analysis of apoptotic level of HepG2 and SMMC-7721 cells with tBHP administration and/or sh-ADAR1 transfection. **p < 0.01; ***p < 0.001; ****p < 0.0001Back to article page