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Fig. 6 | Experimental Hematology & Oncology

Fig. 6

From: Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins

Fig. 6

LAMP5-AS1-LAMP5 axis regulates autophagic flux. siRNAs targeting LAMP5-AS1 and LAMP5 were transient transfected into stable mRFP-GFP-LC3 THP1 cells which were treated with or without bafilomycin A1 (25 nM, 12 h). Scale bar, 10 μm. The numbers of yellow LC3 puncta and red LC3 puncta per cell in each condition were quantified using Image-Pro Plus. Total LC3 puncta represent the number of yellow LC3 puncta and red LC3 puncta. More than 20 cells were counted in each condition (Mean ± SEM)

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Experimental Hematology & Oncology

ISSN: 2162-3619

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