Fig. 1

METTL1/WDR4 were upregulated and associated with poor prognosis of AML patients. A Expression Level of METTL1 and WDR4 in healthy individuals (NC) and AML patients from the GEO dataset. B Comparison of METTL1 and WDR4 expression in bone marrow (BM) and peripheral blood (PB) samples between AML patients (red box) and healthy individuals (blue box) from the GEO dataset. C Expression level of METTL1 and WDR4 in bone marrow mononuclear cells between healthy donors (NC) and AML patients from our center. D Comparison of METTL1 and WDR4 expression in healthy individuals and various subtypes of AML patients in the GEO dataset. E Expression level of METTL1 and WDR4 between healthy donors and various subtypes of AML patients from our center. F Representative bands of METTL1 and WDR4 examined by western blot assay in healthy donors and AML patients from our center. G Correlation between METTL1/WDR4 expression and overall survival of AML patients according to data from TCGA. Data were presented as mean ± SEM (Student’s t test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns: not significant)