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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: ZMIZ2 facilitates hepatocellular carcinoma progression via LEF1 mediated activation of Wnt/β-catenin pathway

Fig. 5

ZMIZ2 enhanced the oncogenesis of HCC cells in vivo. (A-B) Representative images of tumors formed in nude mice injected subcutaneously with the SK-hep1 and SK-hep1-shRNA cells (N = 5). (C) Tumor growth curves in the indicated groups. (D) Assessment of the weight of the dissected tumors. (E) Representative images of IHC staining of ZMIZ2, LEF1, and Ki67 in xenograft tumors. Scale bars: 50 μm. **p < 0.01; ***p < 0.001; **** p < 0.0001

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