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Fig. 3 | Experimental Hematology & Oncology

Fig. 3

From: ZMIZ2 facilitates hepatocellular carcinoma progression via LEF1 mediated activation of Wnt/β-catenin pathway

Fig. 3

ZMIZ2 promotes HCC cell proliferation, migration, and invasion. (A-B) The efficiencies of ZMIZ2 silencing and ZMIZ2 overexpression were validated by qRT-PCR and Western blotting. (C-E) CCK8 assay, Luminescent Cell Viability Assay and EDU assays were performed to identify proliferation after ZMIZ2 knockdown in Huh7 and Hep3B cell, ZMIZ2 overexpression in HepG2 cell. (F-G) Wound healing, migration, and invasion assays were performed to identify metastasis ability after ZMIZ2 knockdown in Huh7 and Hep3B cell and ZMIZ2 overexpression in HepG2 cell. **p < 0.01; ***p < 0.001; **** p < 0.0001

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