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Table 2 Strength of recommendations

From: Chinese expert consensus on Bruton tyrosine kinase inhibitors in the treatment of B-cell malignancies

Category

Description

1

Based upon high-level evidence, there is uniform consensus that the intervention is appropriate

2A

Based upon low-level evidence, there is uniform consensus that the intervention is appropriate

2B

Based upon low-level evidence, there is consensus that the intervention is appropriate

3

Based upon any level of evidence, there is a major disagreement that the intervention is appropriate

  1. For the “uniform consensus” defined in category 1 and category 2A, a majority panel vote of at least 85% is required. For the consensus, defined in category 2B, a panel vote of at least 50% (but < 85%) is required. Lastly, for recommendations where there is a strong panel disagreement regardless of the quality of the evidence, it requires a panel vote of at least 25% to include and designate a recommendation as category 3